A voxel based morphometry study on mild cognitive impairment
نویسندگان
چکیده
منابع مشابه
A voxel based morphometry study on mild cognitive impairment.
BACKGROUND Mild cognitive impairment (MCI) is the most widely used concept in classifying cognitive impairment in the elderly who do not fulfil the criteria for dementia. MCI is considered to confer an increased risk of progressing to dementia and most often Alzheimer's disease (AD). Various approaches such as imaging of the brain have been applied to predict the conversion of MCI to dementia. ...
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Alzheimer’s disease (AD) is the most common cause of dementia in the general population older than 60 years of age [1,2]. The clinical manifestations of AD are seen in the domains of memory and spatial navigation in the early phases of the disease, with almost all cognitive domains affected as the disease progresses, including attention, language, and visuospatial function, as well as executive...
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BACKGROUND AND PURPOSE To assess the neural substrates underlying topographical disorientation (TD) in patients affected by mild cognitive impairment (MCI), forty-one patients diagnosed with MCI and 24 healthy control individuals were recruited. METHODS TD was assessed clinically in all participants. Neurological and neuropsychological evaluations and a volumetric-head magnetic resonance imag...
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Reduced awareness of cognitive deficits in mild cognitive impairment (MCI) is associated with poorer outcomes although little is known about the anatomical correlates of this. We examined the association of insight and grey matter volume using a voxel-based morphometry approach in 65 volunteers with MCI and 55 healthy age-matched controls. Participants with MCI had multiple areas of subtle grey...
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BACKGROUND The aim of the present study was to investigate whether there were differences in neuroradiological features, including white-matter lesions and gray-matter volumes, between patients with lacunar infarction with and without mild cognitive impairment of the vascular type (MCI-V). METHODS A total of 40 patients with lacunar infarction were studied within 1 month after stroke. RESUL...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2005
ISSN: 0022-3050
DOI: 10.1136/jnnp.2004.035600